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1 OMIM reference -
1 associated gene
12 signs/symptoms
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
No signs/symptoms info
Alpha-thalassemia - myelodysplastic syndrome
Adrenocortical carcinoma

ATRX TP53


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
ATRX
(0.63)
TP53



Citations in the biomedical literature:


Alpha-thalassemia - myelodysplastic syndrome
ATRX
Adrenocortical carcinoma
TP53



Alpha-thalassemia - myelodysplastic syndrome
Adrenocortical carcinoma

Synonym(s):
- ATMDS
- Acquired HbH disease
- Acquired hemoglobin H disease

Synonym(s):
(no synonyms)

Classification (Orphanet):
- Rare genetic disease
- Rare hematologic disease
Classification (Orphanet):
- Rare circulatory system disease
- Rare endocrine disease
- Rare infertility
- Rare oncologic disease
- Rare renal disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: adulthood
Average age of death: elderly
Type of inheritance: sporadic
Epidemiological data:
Class of prevalence: 1-9 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: sporadic

External references:
1 OMIM reference -
No MeSH references
External references:
1 OMIM reference -
1 MeSH reference: D018268

Alpha-thalassemia - myelodysplastic syndrome

Very frequent
- Asthenia / fatigue / weakness
- Microcytic anemia
- Myelodysplastic syndrome
- Polynuclear cells / neutrophils anomalies / neutropenia
- Thrombocytopenia / thrombopenia

Frequent
- Bruisability
- Hemorrhage / hemorrhagic syndrome / excessive / long-lasting bleeding
- Respiratory distress / dyspnea / respiratory failure / lung volume reduction

Occasional
- Acute leukemia
- Immunodeficiency / increased susceptibility to infections / recurrent infections
- Neoplasms / tumors
- Splenomegaly


Adrenocortical carcinoma

(no data available)